Roundcube gets 500 error when Enable iptables

[kardoqadir]

I have checked the sever the iptables is disabled , when I restarted it everything works fine but the roundcube mail show 500 error.. I have check the logs that is the messages

Code: Select all

2019/07/31 18:36:14 [error] 2305#2305: *148 upstream timed out (110: Connection timed out) while reading response header from upstream, client: [IP], server: [DOMAIN], request: "GET /webmail/?_task=mail&_mbox=Sent HTTP/1.1", upstream: "fastcgi://127.0.0.1:9000", host: "[DOMAIN]", referrer: "https://[DOMAIN]/webmail/?_task=mail&_refresh=1&_mbox=Sent"

what is the problem?